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Human POLD1 modulates cell cycle progression and DNA damage repair

BACKGROUND: The activity of eukaryotic DNA polymerase delta (Pol δ) plays an essential role in genome stability through its effects on DNA replication and repair. The p125 catalytic subunit of Pol δ is encoded by POLD1 gene in human cells. To clarify biological functions of POLD1, we investigated th...

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Detalles Bibliográficos
Autores principales:	Song, Jing, Hong, Ping, Liu, Chengeng, Zhang, Yueqi, Wang, Jinling, Wang, Peichang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471906/ https://www.ncbi.nlm.nih.gov/pubmed/26087769 http://dx.doi.org/10.1186/s12858-015-0044-7

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