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Impact of autoimmune risk alleles on the immune system

Genetic analyses of autoimmune diseases have revealed hundreds of disease-associated DNA variants, but the identity and function of the causal variants are understudied and warrant deeper mechanistic studies. Here, we highlight methods for deciphering how alleles that are associated with autoimmune...

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Detalles Bibliográficos
Autores principales: Ray, John P, Hacohen, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471922/
https://www.ncbi.nlm.nih.gov/pubmed/26089985
http://dx.doi.org/10.1186/s13073-015-0182-y