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Cyclin-dependent kinase 5 acts as a critical determinant of AKT-dependent proliferation and regulates differential gene expression by the androgen receptor in prostate cancer cells

Contrary to cell cycle–associated cyclin-dependent kinases, CDK5 is best known for its regulation of signaling processes in differentiated cells and its destructive activation in Alzheimer's disease. Recently, CDK5 has been implicated in a number of different cancers, but how it is able to stim...

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Detalles Bibliográficos
Autores principales: Lindqvist, Julia, Imanishi, Susumu Y., Torvaldson, Elin, Malinen, Marjo, Remes, Mika, Örn, Fanny, Palvimo, Jorma J., Eriksson, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472009/
https://www.ncbi.nlm.nih.gov/pubmed/25851605
http://dx.doi.org/10.1091/mbc.E14-12-1634