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Chromatids segregate without centrosomes during Caenorhabditis elegans mitosis in a Ran- and CLASP-dependent manner

During mitosis, chromosomes are connected to a microtubule-based spindle. Current models propose that displacement of the spindle poles and/or the activity of kinetochore microtubules generate mechanical forces that segregate sister chromatids. Using laser destruction of the centrosomes during Caeno...

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Detalles Bibliográficos
Autores principales: Nahaboo, Wallis, Zouak, Melissa, Askjaer, Peter, Delattre, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472013/
https://www.ncbi.nlm.nih.gov/pubmed/25833711
http://dx.doi.org/10.1091/mbc.E14-12-1577