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Sorting nexin 27 regulates basal and stimulated brush border trafficking of NHE3

Sorting nexin 27 (SNX27) contains a PDZ domain that is phylogenetically related to the PDZ domains of the NHERF proteins. Studies on nonepithelial cells have shown that this protein is located in endosomes, where it regulates trafficking of cargo proteins in a PDZ domain–dependent manner. However, t...

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Detalles Bibliográficos
Autores principales: Singh, Varsha, Yang, Jianbo, Cha, Boyoung, Chen, Tiane-e, Sarker, Rafiquel, Yin, Jianyi, Avula, Leela Rani, Tse, Ming, Donowitz, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472014/
https://www.ncbi.nlm.nih.gov/pubmed/25851603
http://dx.doi.org/10.1091/mbc.E14-12-1597