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Pat1 protects centromere-specific histone H3 variant Cse4 from Psh1-mediated ubiquitination

Evolutionarily conserved histone H3 variant Cse4 and its homologues are essential components of specialized centromere (CEN)-specific nucleosomes and serve as an epigenetic mark for CEN identity and propagation. Cse4 is a critical determinant for the structure and function of the kinetochore and is...

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Detalles Bibliográficos
Autores principales: Mishra, Prashant K., Guo, Jiasheng, Dittman, Lauren E., Haase, Julian, Yeh, Elaine, Bloom, Kerry, Basrai, Munira A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472017/
https://www.ncbi.nlm.nih.gov/pubmed/25833709
http://dx.doi.org/10.1091/mbc.E14-08-1335