The human 18S rRNA base methyltransferases DIMT1L and WBSCR22-TRMT112 but not rRNA modification are required for ribosome biogenesis

At the heart of the ribosome lie rRNAs, whose catalytic function in translation is subtly modulated by posttranscriptional modifications. In the small ribosomal subunit of budding yeast, on the 18S rRNA, two adjacent adenosines (A1781/A1782) are N(6)-dimethylated by Dim1 near the decoding site, and...

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Detalles Bibliográficos
Autores principales: Zorbas, Christiane, Nicolas, Emilien, Wacheul, Ludivine, Huvelle, Emmeline, Heurgué-Hamard, Valérie, Lafontaine, Denis L. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472018/
https://www.ncbi.nlm.nih.gov/pubmed/25851604
http://dx.doi.org/10.1091/mbc.E15-02-0073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472018/
https://www.ncbi.nlm.nih.gov/pubmed/25851604
http://dx.doi.org/10.1091/mbc.E15-02-0073

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