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Twitchin kinase interacts with MAPKAP kinase 2 in Caenorhabditis elegans striated muscle

In Caenorhabditis elegans, twitchin is a giant polypeptide located in muscle A-bands. The protein kinase of twitchin is autoinhibited by 45 residues upstream (NL) and 60 residues downstream (CRD) of the kinase catalytic core. Molecular dynamics simulation on a twitchin fragment revealed that the NL...

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Detalles Bibliográficos
Autores principales: Matsunaga, Yohei, Qadota, Hiroshi, Furukawa, Miho, Choe, Heejoo (Helen), Benian, Guy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472019/
https://www.ncbi.nlm.nih.gov/pubmed/25851606
http://dx.doi.org/10.1091/mbc.E14-05-1009