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Twitchin kinase interacts with MAPKAP kinase 2 in Caenorhabditis elegans striated muscle
In Caenorhabditis elegans, twitchin is a giant polypeptide located in muscle A-bands. The protein kinase of twitchin is autoinhibited by 45 residues upstream (NL) and 60 residues downstream (CRD) of the kinase catalytic core. Molecular dynamics simulation on a twitchin fragment revealed that the NL...
Autores principales: | Matsunaga, Yohei, Qadota, Hiroshi, Furukawa, Miho, Choe, Heejoo (Helen), Benian, Guy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472019/ https://www.ncbi.nlm.nih.gov/pubmed/25851606 http://dx.doi.org/10.1091/mbc.E14-05-1009 |
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