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The RhoGEF DOCK10 is essential for dendritic spine morphogenesis

By regulating actin cytoskeleton dynamics, Rho GTPases and their activators RhoGEFs are implicated in various aspects of neuronal differentiation, including dendritogenesis and synaptogenesis. Purkinje cells (PCs) of the cerebellum, by developing spectacular dendrites covered with spines, represent...

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Detalles Bibliográficos
Autores principales: Jaudon, Fanny, Raynaud, Fabrice, Wehrlé, Rosine, Bellanger, Jean-Michel, Doulazmi, Mohamed, Vodjdani, Guilan, Gasman, Stéphane, Fagni, Laurent, Dusart, Isabelle, Debant, Anne, Schmidt, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472020/
https://www.ncbi.nlm.nih.gov/pubmed/25851601
http://dx.doi.org/10.1091/mbc.E14-08-1310