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Clinical utility of naloxegol in the treatment of opioid-induced constipation

Opioids are a class of medications frequently used for the treatment of acute and chronic pain, exerting their desired effects at central opioid receptors. Agonism at peripherally located opioid receptors, however, leads to opioid-induced constipation (OIC), one of the most frequent and debilitating...

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Detalles Bibliográficos
Autores principales: Bruner, Heather C, Atayee, Rabia S, Edmonds, Kyle P, Buckholz, Gary T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472065/
https://www.ncbi.nlm.nih.gov/pubmed/26109876
http://dx.doi.org/10.2147/JPR.S61326