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Clinical utility of naloxegol in the treatment of opioid-induced constipation
Opioids are a class of medications frequently used for the treatment of acute and chronic pain, exerting their desired effects at central opioid receptors. Agonism at peripherally located opioid receptors, however, leads to opioid-induced constipation (OIC), one of the most frequent and debilitating...
Autores principales: | Bruner, Heather C, Atayee, Rabia S, Edmonds, Kyle P, Buckholz, Gary T |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472065/ https://www.ncbi.nlm.nih.gov/pubmed/26109876 http://dx.doi.org/10.2147/JPR.S61326 |
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