Reduced EGFR signaling enhances cartilage destruction in a mouse osteoarthritis model

Osteoarthritis (OA) is a degenerative joint disease and a major cause of pain and disability in older adults. We have previously identified epidermal growth factor receptor (EGFR) signaling as an important regulator of cartilage matrix degradation during epiphyseal cartilage development. To study it...

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Detalles Bibliográficos
Autores principales: Zhang, Xianrong, Zhu, Ji, Liu, Fei, Li, Yumei, Chandra, Abhishek, Levin, L Scott, Beier, Frank, Enomoto-Iwamoto, Motomi, Qin, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472123/
https://www.ncbi.nlm.nih.gov/pubmed/26120493
http://dx.doi.org/10.1038/boneres.2014.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472123/
https://www.ncbi.nlm.nih.gov/pubmed/26120493
http://dx.doi.org/10.1038/boneres.2014.15

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