Hypoxia-inducible factor-1α restricts the anabolic actions of parathyroid hormone

The hypoxia inducible factors (Hifs) are evolutionarily conserved transcriptional factors that control homeostatic responses to low oxygen. In developing bone, Hif-1 generated signals induce angiogenesis necessary for osteoblast specification, but in mature bone, loss of Hif-1 in osteoblasts resulte...

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Detalles Bibliográficos
Autores principales: Frey, Julie L, Stonko, David P, Faugere, Marie-Claude, Riddle, Ryan C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472139/
https://www.ncbi.nlm.nih.gov/pubmed/26273518
http://dx.doi.org/10.1038/boneres.2014.5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472139/
https://www.ncbi.nlm.nih.gov/pubmed/26273518
http://dx.doi.org/10.1038/boneres.2014.5

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