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In vivo evidence of IGF-I–estrogen crosstalk in mediating the cortical bone response to mechanical strain

Although insulin-like growth factor-I (IGF-I) and estrogen signaling pathways have been shown to be involved in mediating the bone anabolic response to mechanical loading, it is not known whether these two signaling pathways crosstalk with each other in producing a skeletal response to mechanical lo...

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Detalles Bibliográficos
Autores principales: Mohan, Subburaman, Bhat, Chetan Girijanand, Wergedal, Jon E, Kesavan, Chandrasekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472140/
https://www.ncbi.nlm.nih.gov/pubmed/26273520
http://dx.doi.org/10.1038/boneres.2014.7