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(99m)TC-Methylene diphosphonate uptake at injury site correlates with osteoblast differentiation and mineralization during bone healing in mice

(99m)Tc-Methylene diphosphonate ((99m)Tc-MDP) is widely used in clinical settings to detect bone abnormalities. However, the mechanism of (99m)Tc-MDP uptake in bone is not well elucidated. In this study, we utilized a mouse tibia injury model, single-photon emission computed tomography (gamma scinti...

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Detalles Bibliográficos
Autores principales: Zhong, Zhendong A, Peck, Anderson, Li, Shihong, VanOss, Jeff, Snider, John, Droscha, Casey J, Chang, Tingtung A, Williams, Bart O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472149/
https://www.ncbi.nlm.nih.gov/pubmed/26273540
http://dx.doi.org/10.1038/boneres.2015.13