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MicroRNA-26b inhibits cell proliferation and cytokine secretion in human RASF cells via the Wnt/GSK-3β/β-catenin pathway

BACKGROUND: Rheumatoid arthritis (RA) is a chronic systemic auto- immune disease characterized by joint synovitis. Recent evidence suggests that rheumatoid arthritis synovial fibroblasts (RASFs) promote joint destruction. In this study, we investigated the role of microRNA-26b (miR-26b) in cell prol...

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Detalles Bibliográficos
Autores principales: Sun, Jiling, Yan, Peng, Chen, Yuanzheng, Chen, Yang, Yang, Jianxun, Xu, Guangyue, Mao, Haijun, Qiu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472173/
https://www.ncbi.nlm.nih.gov/pubmed/26088648
http://dx.doi.org/10.1186/s13000-015-0309-x