DNA mismatch repair deficiency accelerates lung neoplasm development in K-ras(LA1/+) mice: a brief report

Inherited as well as acquired deficiencies in specific DNA mismatch repair (MMR) components are associated with the development of a wide range of benign and malignant neoplasms. Loss of key members such as MSH2 and MLH1 severely cripples the ability of the cell to recognize and correct such lesions...

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Detalles Bibliográficos
Autores principales: Downey, Charlene M, Jirik, Frank R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472212/
https://www.ncbi.nlm.nih.gov/pubmed/25773971
http://dx.doi.org/10.1002/cam4.420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472212/
https://www.ncbi.nlm.nih.gov/pubmed/25773971
http://dx.doi.org/10.1002/cam4.420

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