Immunogens Modeling a Fusion-Intermediate Conformation of gp41 Elicit Antibodies to the Membrane Proximal External Region of the HIV Envelope Glycoprotein

The membrane proximal external region (MPER) of the gp41 subunit of the HIV-1 envelope glycoprotein (Env) contains determinants for broadly neutralizing antibodies and has remained an important focus of vaccine design. However, creating an immunogen that elicits broadly neutralizing antibodies to th...

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Detalles Bibliográficos
Autores principales: Vassell, Russell, He, Yong, Vennakalanti, Prasad, Dey, Antu K., Zhuang, Min, Wang, Wei, Sun, Yide, Biron-Sorek, Zohar, Srivastava, Indresh K., LaBranche, Celia C., Montefiori, David C., Barnett, Susan W., Weiss, Carol D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472232/
https://www.ncbi.nlm.nih.gov/pubmed/26087072
http://dx.doi.org/10.1371/journal.pone.0128562

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472232/
https://www.ncbi.nlm.nih.gov/pubmed/26087072
http://dx.doi.org/10.1371/journal.pone.0128562

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