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Passive targeting of thermosensitive diblock copolymer micelles to the lungs: synthesis and characterization of poly(N-isopropylacrylamide)-block-poly(ε-caprolactone)

BACKGROUND: Amphiphilic poly(N-isopropylacrylamide)-block-poly(ε-caprolactone) (PNiPAAm-b-PCL) copolymers were synthesized by ring-opening polymerization to form thermosensitive micelles as nanocarriers for bioimaging and carboplatin delivery. RESULTS: The critical micelle concentration increased fr...

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Detalles Bibliográficos
Autores principales: Lee, Ren-Shen, Lin, Chih-Hung, Aljuffali, Ibrahim A, Hu, Kai-Yin, Fang, Jia-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472254/
https://www.ncbi.nlm.nih.gov/pubmed/26084491
http://dx.doi.org/10.1186/s12951-015-0103-7