α7 and β2 Nicotinic Acetylcholine Receptor Subunits Form Heteromeric Receptor Complexes that Are Expressed in the Human Cortex and Display Distinct Pharmacological Properties

The existence of α7β2 nicotinic acetylcholine receptors (nAChRs) has recently been demonstrated in both the rodent and human brain. Since α7-containing nAChRs are promising drug targets for schizophrenia and Alzheimer’s disease, it is critical to determine whether α7β2 nAChRs are present in the huma...

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Detalles Bibliográficos
Autores principales: Thomsen, Morten Skøtt, Zwart, Ruud, Ursu, Daniel, Jensen, Majbrit Myrup, Pinborg, Lars Hageman, Gilmour, Gary, Wu, Jie, Sher, Emanuele, Mikkelsen, Jens Damsgaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472343/
https://www.ncbi.nlm.nih.gov/pubmed/26086615
http://dx.doi.org/10.1371/journal.pone.0130572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472343/
https://www.ncbi.nlm.nih.gov/pubmed/26086615
http://dx.doi.org/10.1371/journal.pone.0130572

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