Mitochondrial Dysfunction Induced by N-Butyl-1-(4-Dimethylamino)Phenyl-1,2,3,4-Tetrahydro-β-Carboline-3-Carboxamide Is Required for Cell Death of Trypanosoma cruzi

BACKGROUND: Chagas’ disease is caused by the protozoan Trypanosoma cruzi and affects thousands of people worldwide. The available treatments are unsatisfactory, and new drugs must be developed. Our group recently reported the trypanocidal activity of the synthetic compound N-butyl-1-(4-dimethylamino...

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Detalles Bibliográficos
Autores principales: Volpato, Hélito, Desoti, Vânia Cristina, Valdez, Rodrigo Hinojosa, Ueda-Nakamura, Tânia, Silva, Sueli de Oliveira, Sarragiotto, Maria Helena, Nakamura, Celso Vataru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472351/
https://www.ncbi.nlm.nih.gov/pubmed/26086449
http://dx.doi.org/10.1371/journal.pone.0130652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472351/
https://www.ncbi.nlm.nih.gov/pubmed/26086449
http://dx.doi.org/10.1371/journal.pone.0130652

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