Dynamic pathways of -1 translational frameshifting

Spontaneous changes in the reading frame of translation are rare (frequency of 10(−3) – 10(−4) per codon)(1), but can be induced by specific features in the messenger RNA (mRNA). In the presence of mRNA secondary structures, a heptanucleotide “slippery sequence” usually defined by the motif X XXY YY...

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Detalles Bibliográficos
Autores principales: Chen, Jin, Petrov, Alexey, Johansson, Magnus, Tsai, Albert, O’Leary, Seán E., Puglisi, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472451/
https://www.ncbi.nlm.nih.gov/pubmed/24919156
http://dx.doi.org/10.1038/nature13428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472451/
https://www.ncbi.nlm.nih.gov/pubmed/24919156
http://dx.doi.org/10.1038/nature13428

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