Cargando…
Dynamic pathways of -1 translational frameshifting
Spontaneous changes in the reading frame of translation are rare (frequency of 10(−3) – 10(−4) per codon)(1), but can be induced by specific features in the messenger RNA (mRNA). In the presence of mRNA secondary structures, a heptanucleotide “slippery sequence” usually defined by the motif X XXY YY...
Autores principales: | Chen, Jin, Petrov, Alexey, Johansson, Magnus, Tsai, Albert, O’Leary, Seán E., Puglisi, Joseph D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472451/ https://www.ncbi.nlm.nih.gov/pubmed/24919156 http://dx.doi.org/10.1038/nature13428 |
Ejemplares similares
-
Coordinated conformational and compositional dynamics drive ribosome translocation
por: Chen, Jin, et al.
Publicado: (2013) -
N(6)-methyladenosine in mRNA disrupts tRNA selection and translation elongation dynamics
por: Choi, Junhong, et al.
Publicado: (2016) -
Heterogeneous Pathways and Timing of Factor Departure during Translation Initiation
por: Tsai, Albert, et al.
Publicado: (2012) -
The energy landscape of −1 ribosomal frameshifting
por: Choi, Junhong, et al.
Publicado: (2020) -
mRNA- and factor-driven dynamic variability controls eIF4F-cap recognition for translation initiation
por: Çetin, Burak, et al.
Publicado: (2022)