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Listeriolysin O Affects the Permeability of Caco-2 Monolayer in a Pore-Dependent and Ca(2+)-Independent Manner

Listeria monocytogenes is a food and soil-borne pathogen that secretes a pore-forming toxin listeriolysin O (LLO) as its major virulence factor. We tested the effects of LLO on an intestinal epithelial cell line Caco-2 and compared them to an unrelated pore-forming toxin equinatoxin II (EqtII). Resu...

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Detalles Bibliográficos
Autores principales: Cajnko, Miša Mojca, Marušić, Maja, Kisovec, Matic, Rojko, Nejc, Benčina, Mojca, Caserman, Simon, Anderluh, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472510/
https://www.ncbi.nlm.nih.gov/pubmed/26087154
http://dx.doi.org/10.1371/journal.pone.0130471