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Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth
BACKGROUND: There is growing evidence that emerging malignancies in solid tissues might be kept under control by physical intercellular contacts with normal fibroblasts. METHODS: Here we characterize transcriptional landscapes of fibroblasts that confronted cancer cells. We studied four pairs of in...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472614/ https://www.ncbi.nlm.nih.gov/pubmed/26081588 http://dx.doi.org/10.1186/s13046-015-0178-x |