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Confrontation of fibroblasts with cancer cells in vitro: gene network analysis of transcriptome changes and differential capacity to inhibit tumor growth

BACKGROUND: There is growing evidence that emerging malignancies in solid tissues might be kept under control by physical intercellular contacts with normal fibroblasts. METHODS: Here we characterize transcriptional landscapes of fibroblasts that confronted cancer cells. We studied four pairs of in...

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Detalles Bibliográficos
Autores principales: Alexeyenko, Andrey, Alkasalias, Twana, Pavlova, Tatiana, Szekely, Laszlo, Kashuba, Vladimir, Rundqvist, Helene, Wiklund, Peter, Egevad, Lars, Csermely, Peter, Korcsmaros, Tamas, Guven, Hayrettin, Klein, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472614/
https://www.ncbi.nlm.nih.gov/pubmed/26081588
http://dx.doi.org/10.1186/s13046-015-0178-x