Dexamethasone and BCAA Failed to Modulate Muscle Mass and mTOR Signaling in GH-Deficient Rats

Branched-chain amino acids (BCAAs) and IGF-I, the secretion of which is stimulated by growth hormone (GH), prevent muscle atrophy. mTOR plays a pivotal role in the protective actions of BCAA and IGF-1. The pathway by which BCAA activates mTOR is different from that of IGF-1, which suggests that BCAA...

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Detalles Bibliográficos
Autores principales: Nishida, Hikaru, Ikegami, Ayaka, Kaneko, Chiaki, Kakuma, Hitomi, Nishi, Hisano, Tanaka, Noriko, Aoyama, Michiko, Usami, Makoto, Okimura, Yasuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472719/
https://www.ncbi.nlm.nih.gov/pubmed/26086773
http://dx.doi.org/10.1371/journal.pone.0128805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472719/
https://www.ncbi.nlm.nih.gov/pubmed/26086773
http://dx.doi.org/10.1371/journal.pone.0128805

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