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High Inter-Individual Diversity of Point Mutations, Insertions, and Deletions in Human Influenza Virus Nucleoprotein-Specific Memory B Cells

The diversity of virus-specific antibodies and of B cells among different individuals is unknown. Using single-cell cloning of antibody genes, we generated recombinant human monoclonal antibodies from influenza nucleoprotein-specific memory B cells in four adult humans with and without preceding inf...

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Detalles Bibliográficos
Autores principales: Reiche, Sven, Dwai, Yamen, Bussmann, Bianca M., Horn, Susanne, Sieg, Michael, Jassoy, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472751/
https://www.ncbi.nlm.nih.gov/pubmed/26086076
http://dx.doi.org/10.1371/journal.pone.0128684