Towards Antiviral shRNAs Based on the AgoshRNA Design

RNA interference (RNAi) can be induced by intracellular expression of a short hairpin RNA (shRNA). Processing of the shRNA requires the RNaseIII-like Dicer enzyme to remove the loop and to release the biologically active small interfering RNA (siRNA). Dicer is also involved in microRNA (miRNA) proce...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Ying Poi, Karg, Margarete, Herrera-Carrillo, Elena, Berkhout, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472832/
https://www.ncbi.nlm.nih.gov/pubmed/26087209
http://dx.doi.org/10.1371/journal.pone.0128618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472832/
https://www.ncbi.nlm.nih.gov/pubmed/26087209
http://dx.doi.org/10.1371/journal.pone.0128618

Ejemplares similares