AECHL-1, a novel triterpenoid, targets tumor neo-vasculature and impairs the endothelial cell cytoskeleton

Tumor angiogenesis is characterized by abnormal vessel morphology leading to erratic and insufficient delivery of chemotherapeutics and oxygen, making the tumor core not only highly hypoxic but also unresponsive toward treatment. Such hypoxic conditions promote tumor aggressiveness, leading to the e...

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Detalles Bibliográficos
Autores principales: Dasgupta, Aparajita, Sawant, Mithila A., Lavhale, Manish S., Krishnapati, Lakshmi-Surekha, Ghaskadbi, Surendra, Sitasawad, Sandhya L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472952/
https://www.ncbi.nlm.nih.gov/pubmed/25952529
http://dx.doi.org/10.1007/s10456-015-9466-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472952/
https://www.ncbi.nlm.nih.gov/pubmed/25952529
http://dx.doi.org/10.1007/s10456-015-9466-5

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