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Human islet function following 20 years of cryogenic biobanking

AIMS/HYPOTHESIS: There are potential advantages to the low-temperature (−196°C) banking of isolated islets, including the maintenance of viable islets for future research. We therefore assessed the in vitro and in vivo function of islets cryopreserved for nearly 20 years. METHODS: Human islets were...

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Detalles Bibliográficos
Autores principales: Manning Fox, Jocelyn E., Lyon, James, Dai, Xiao Qing, Wright, Robert C., Hayward, Julie, van de Bunt, Martijn, Kin, Tatsuya, Shapiro, A. M. James, McCarthy, Mark I., Gloyn, Anna L., Ungrin, Mark D., Lakey, Jonathan R., Kneteman, Norm M., Warnock, Garth L., Korbutt, Gregory S., Rajotte, Raymond V., MacDonald, Patrick E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4472956/
https://www.ncbi.nlm.nih.gov/pubmed/25930156
http://dx.doi.org/10.1007/s00125-015-3598-4