Maleic Acid – but Not Structurally Related Methylmalonic Acid – Interrupts Energy Metabolism by Impaired Calcium Homeostasis

Maleic acid (MA) has been shown to induce Fanconi syndrome via disturbance of renal energy homeostasis, though the underlying pathomechanism is still under debate. Our study aimed to examine the pathomechanism underlying maleic acid-induced nephrotoxicity. Methylmalonic acid (MMA) is structurally si...

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Detalles Bibliográficos
Autores principales: Tuncel, Ali Tunç, Ruppert, Thorsten, Wang, Bei-Tzu, Okun, Jürgen Günther, Kölker, Stefan, Morath, Marina Alexandra, Sauer, Sven Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473014/
https://www.ncbi.nlm.nih.gov/pubmed/26086473
http://dx.doi.org/10.1371/journal.pone.0128770

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473014/
https://www.ncbi.nlm.nih.gov/pubmed/26086473
http://dx.doi.org/10.1371/journal.pone.0128770

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