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Intra-ventral tegmental area HIV-1 Tat(1–86) attenuates nicotine-mediated locomotor sensitization and alters mesocorticolimbic ERK and CREB signaling in rats

Cigarette smoking prevalence in the HIV-positive individuals is profoundly higher than that in the HIV-negative individuals. We have demonstrated that HIV-1 transgenic rats exhibit attenuated nicotine-mediated locomotor activity, altered cAMP response element binding protein (CREB) and extracellular...

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Detalles Bibliográficos
Autores principales: Zhu, Jun, Midde, Narasimha M., Gomez, Adrian M., Sun, Wei-Lun, Harrod, Steven B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473058/
https://www.ncbi.nlm.nih.gov/pubmed/26150803
http://dx.doi.org/10.3389/fmicb.2015.00540