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Increased Expression of Simple Ganglioside Species GM2 and GM3 Detected by MALDI Imaging Mass Spectrometry in a Combined Rat Model of Aβ Toxicity and Stroke

The aging brain is often characterized by the presence of multiple comorbidities resulting in synergistic damaging effects in the brain as demonstrated through the interaction of Alzheimer’s disease (AD) and stroke. Gangliosides, a family of membrane lipids enriched in the central nervous system, ma...

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Detalles Bibliográficos
Autores principales: Caughlin, Sarah, Hepburn, Jeffrey D., Park, Dae Hee, Jurcic, Kristina, Yeung, Ken K.-C., Cechetto, David F., Whitehead, Shawn N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473074/
https://www.ncbi.nlm.nih.gov/pubmed/26086081
http://dx.doi.org/10.1371/journal.pone.0130364