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Evolution of an Enzyme from a Noncatalytic Nucleic Acid Sequence

The mechanism by which enzymes arose from both abiotic and biological worlds remains an unsolved natural mystery. We postulate that an enzyme can emerge from any sequence of any functional polymer under permissive evolutionary conditions. To support this premise, we have arbitrarily chosen a 50-nucl...

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Detalles Bibliográficos
Autores principales: Gysbers, Rachel, Tram, Kha, Gu, Jimmy, Li, Yingfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473686/
https://www.ncbi.nlm.nih.gov/pubmed/26091540
http://dx.doi.org/10.1038/srep11405