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The lysophosphatidic acid receptor LPA(4) regulates hematopoiesis-supporting activity of bone marrow stromal cells

Lysophosphatidic acid (LPA) is a pleiotropic lipid mediator that acts through G protein-coupled receptors (LPA(1-6)). Although several biological roles of LPA(4) are becoming apparent, its role in hematopoiesis has remained unknown. Here, we show a novel regulatory role for LPA(4) in hematopoiesis....

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Detalles Bibliográficos
Autores principales: Igarashi, Hidemitsu, Akahoshi, Noriyuki, Ohto-Nakanishi, Takayo, Yasuda, Daisuke, Ishii, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473687/
https://www.ncbi.nlm.nih.gov/pubmed/26090649
http://dx.doi.org/10.1038/srep11410