Acidic pH and divalent cation sensing by PhoQ are dispensable for systemic salmonellae virulence

Salmonella PhoQ is a histidine kinase with a periplasmic sensor domain (PD) that promotes virulence by detecting the macrophage phagosome. PhoQ activity is repressed by divalent cations and induced in environments of acidic pH, limited divalent cations, and cationic antimicrobial peptides (CAMP). Pr...

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Detalles Bibliográficos
Autores principales: Hicks, Kevin G, Delbecq, Scott P, Sancho-Vaello, Enea, Blanc, Marie-Pierre, Dove, Katja K, Prost, Lynne R, Daley, Margaret E, Zeth, Kornelius, Klevit, Rachel E, Miller, Samuel I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473727/
https://www.ncbi.nlm.nih.gov/pubmed/26002083
http://dx.doi.org/10.7554/eLife.06792

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4473727/
https://www.ncbi.nlm.nih.gov/pubmed/26002083
http://dx.doi.org/10.7554/eLife.06792

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