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Targeting matrix metalloproteinases in cancer: Bringing new life to old ideas

Since the identification of matrix metalloproteinases (MMPs), a family of zinc-dependent endopeptidases, as being a driving factor for cancer progression and patient prognosis, MMPs have been studied extensively. Although early programs targeting MMPs were largely unsuccessful in clinical trials, th...

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Detalles Bibliográficos
Autores principales: Cathcart, Jillian, Pulkoski-Gross, Ashleigh, Cao, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474140/
https://www.ncbi.nlm.nih.gov/pubmed/26097889
http://dx.doi.org/10.1016/j.gendis.2014.12.002