Identification and functional prediction of mitochondrial complex III and IV mutations associated with glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common primary brain tumor in adults, with a dismal prognosis. Treatment is hampered by GBM's unique biology, including differential cell response to therapy. Although several mitochondrial abnormalities have been identified, how mitochondrial DNA (mtD...

Descripción completa

Detalles Bibliográficos
Autores principales: Lloyd, Rhiannon E., Keatley, Kathleen, Littlewood, D. Timothy J., Meunier, Brigitte, Holt, William V., An, Qian, Higgins, Samantha C., Polyzoidis, Stavros, Stephenson, Katie F., Ashkan, Keyoumars, Fillmore, Helen L., Pilkington, Geoffrey J., McGeehan, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474231/
https://www.ncbi.nlm.nih.gov/pubmed/25731774
http://dx.doi.org/10.1093/neuonc/nov020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474231/
https://www.ncbi.nlm.nih.gov/pubmed/25731774
http://dx.doi.org/10.1093/neuonc/nov020

Ejemplares similares