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A Novel High-Throughput Technique for Identifying Monoclonal Antibodies Capable of Death Receptor Induced Apoptosis

The study of death receptor family induced apoptosis has gained momentum in recent years with the knowledge that therapeutic antibodies targeting DR4 and DR5 (death receptor’s 4 and 5) have proved efficacious in multiple clinical trials. The therapeutic rationale is based on targeting and amplifying...

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Detalles Bibliográficos
Autores principales: Kwok, Hang Fai, Gormley, Julie A., Scott, Christopher J., Johnston, James A., Olwill, Shane A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474333/
https://www.ncbi.nlm.nih.gov/pubmed/26124680