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ATP Depletion Via Mitochondrial F(1)F(0) Complex by Lethal Factor is an Early Event in B. Anthracis-Induced Sudden Cell Death
Bacillus anthracis’ primary virulence factor is a tripartite anthrax toxin consisting of edema factor (EF), lethal factor (LF) and protective antigen (PA). In complex with PA, EF and LF are internalized via receptor-mediated endocytosis. EF is a calmodulin-dependent adenylate cyclase that induces ti...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474334/ https://www.ncbi.nlm.nih.gov/pubmed/26124678 |