Cargando…

ATP Depletion Via Mitochondrial F(1)F(0) Complex by Lethal Factor is an Early Event in B. Anthracis-Induced Sudden Cell Death

Bacillus anthracis’ primary virulence factor is a tripartite anthrax toxin consisting of edema factor (EF), lethal factor (LF) and protective antigen (PA). In complex with PA, EF and LF are internalized via receptor-mediated endocytosis. EF is a calmodulin-dependent adenylate cyclase that induces ti...

Descripción completa

Detalles Bibliográficos
Autores principales: Woodberry, Mitchell W., Aguilera-Aguirre, Leopoldo, Bacsi, Attila, Chopra, Ashok K., Kurosky, Alexander, Peterson, Johnny W., Boldogh, Istvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474334/
https://www.ncbi.nlm.nih.gov/pubmed/26124678