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MOST+: A de novo motif finding approach combining genomic sequence and heterogeneous genome-wide signatures

BACKGROUND: Motifs are regulatory elements that will activate or inhibit the expression of related genes when proteins (such as transcription factors, TFs) bind to them. Therefore, motif finding is important to understand the mechanisms of gene regulation. De novo discovery of regulatory elements, l...

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Detalles Bibliográficos
Autores principales: Zhang, Yizhe, He, Yupeng, Zheng, Guangyong, Wei, Chaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474412/
https://www.ncbi.nlm.nih.gov/pubmed/26099518
http://dx.doi.org/10.1186/1471-2164-16-S7-S13