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Quetiapine mitigates the ethanol-induced oxidative stress in brain tissue, but not in the liver, of the rat

Quetiapine, an atypical antipsychotic, has been employed to treat alcoholic patients with comorbid psychopathology. It was shown to scavenge hydroxyl radicals and to protect cultured cells from noxious effects of oxidative stress, a pathophysiological mechanism involved in the toxicity of alcohol. T...

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Detalles Bibliográficos
Autores principales: Han, Jin-hong, Tian, Hong-zhao, Lian, Yang-yang, Yu, Yi, Lu, Cheng-biao, Li, Xin-min, Zhang, Rui-ling, Xu, Haiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474454/
https://www.ncbi.nlm.nih.gov/pubmed/26109862
http://dx.doi.org/10.2147/NDT.S80505