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Quetiapine mitigates the ethanol-induced oxidative stress in brain tissue, but not in the liver, of the rat
Quetiapine, an atypical antipsychotic, has been employed to treat alcoholic patients with comorbid psychopathology. It was shown to scavenge hydroxyl radicals and to protect cultured cells from noxious effects of oxidative stress, a pathophysiological mechanism involved in the toxicity of alcohol. T...
Autores principales: | Han, Jin-hong, Tian, Hong-zhao, Lian, Yang-yang, Yu, Yi, Lu, Cheng-biao, Li, Xin-min, Zhang, Rui-ling, Xu, Haiyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474454/ https://www.ncbi.nlm.nih.gov/pubmed/26109862 http://dx.doi.org/10.2147/NDT.S80505 |
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