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Sox2, Tlx, Gli3, and Her9 converge on Rx2 to define retinal stem cells in vivo

Transcriptional networks defining stemness in adult neural stem cells (NSCs) are largely unknown. We used the proximal cis-regulatory element (pCRE) of the retina-specific homeobox gene 2 (rx2) to address such a network. Lineage analysis in the fish retina identified rx2 as marker for multipotent NS...

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Detalles Bibliográficos
Autores principales: Reinhardt, Robert, Centanin, Lázaro, Tavhelidse, Tinatini, Inoue, Daigo, Wittbrodt, Beate, Concordet, Jean-Paul, Martinez-Morales, Juan Ramón, Wittbrodt, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474531/
https://www.ncbi.nlm.nih.gov/pubmed/25908840
http://dx.doi.org/10.15252/embj.201490706