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A weighted and integrated drug-target interactome: drug repurposing for schizophrenia as a use case

BACKGROUND: Computational pharmacology can uniquely address some issues in the process of drug development by providing a macroscopic view and a deeper understanding of drug action. Specifically, network-assisted approach is promising for the inference of drug repurposing. However, the drug-target a...

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Detalles Bibliográficos
Autores principales: Huang, Liang-Chin, Soysal, Ergin, Zheng, W Jim, Zhao, Zhongming, Xu, Hua, Sun, Jingchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474536/
https://www.ncbi.nlm.nih.gov/pubmed/26100720
http://dx.doi.org/10.1186/1752-0509-9-S4-S2