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Oncogenes and tumor suppressor genes: comparative genomics and network perspectives

BACKGROUND: Defective tumor suppressor genes (TSGs) and hyperactive oncogenes (OCGs) heavily contribute to cell proliferation and apoptosis during cancer development through genetic variations such as somatic mutations and deletions. Moreover, they usually do not perform their cellular functions ind...

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Detalles Bibliográficos
Autores principales: Zhu, Kevin, Liu, Qi, Zhou, Yubo, Tao, Cui, Zhao, Zhongming, Sun, Jingchun, Xu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474543/
https://www.ncbi.nlm.nih.gov/pubmed/26099335
http://dx.doi.org/10.1186/1471-2164-16-S7-S8