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Oncogenes and tumor suppressor genes: comparative genomics and network perspectives
BACKGROUND: Defective tumor suppressor genes (TSGs) and hyperactive oncogenes (OCGs) heavily contribute to cell proliferation and apoptosis during cancer development through genetic variations such as somatic mutations and deletions. Moreover, they usually do not perform their cellular functions ind...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474543/ https://www.ncbi.nlm.nih.gov/pubmed/26099335 http://dx.doi.org/10.1186/1471-2164-16-S7-S8 |