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Generation of Multicellular Tumor Spheroids with Microwell-Based Agarose Scaffolds for Drug Testing
Three dimensional multicellular aggregate, also referred to as cell spheroid or microtissue, is an indispensable tool for in vitro evaluating antitumor activity and drug efficacy. Compared with classical cellular monolayer, multicellular tumor spheroid (MCTS) offers a more rational platform to predi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474551/ https://www.ncbi.nlm.nih.gov/pubmed/26090664 http://dx.doi.org/10.1371/journal.pone.0130348 |