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Generation of Multicellular Tumor Spheroids with Microwell-Based Agarose Scaffolds for Drug Testing

Three dimensional multicellular aggregate, also referred to as cell spheroid or microtissue, is an indispensable tool for in vitro evaluating antitumor activity and drug efficacy. Compared with classical cellular monolayer, multicellular tumor spheroid (MCTS) offers a more rational platform to predi...

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Detalles Bibliográficos
Autores principales: Gong, Xue, Lin, Chao, Cheng, Jian, Su, Jiansheng, Zhao, Hang, Liu, Tianlin, Wen, Xuejun, Zhao, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474551/
https://www.ncbi.nlm.nih.gov/pubmed/26090664
http://dx.doi.org/10.1371/journal.pone.0130348