A strain-independent method to induce progressive and lethal pneumococcal pneumonia in neutropenic mice

BACKGROUND: Experimental models of pneumonia with penicillin non-susceptible Streptococcus pneumoniae (PNSSP) are hard to reproduce because the majority of strains with clinical relevance (like serotypes 6B, 9 V and 19 F) have low murine virulence. By optimization of culture and inoculum conditions...

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Detalles Bibliográficos
Autores principales: Zuluaga, Andres F, Salazar, Beatriz E, Agudelo, Maria, Rodriguez, Carlos A, Vesga, Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474571/
https://www.ncbi.nlm.nih.gov/pubmed/25890037
http://dx.doi.org/10.1186/s12929-015-0124-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474571/
https://www.ncbi.nlm.nih.gov/pubmed/25890037
http://dx.doi.org/10.1186/s12929-015-0124-4

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